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Biotech & Genetics · Recorded milestone

Modified mRNA

Recorded year2005

Karikó and Weissman stop synthetic mRNA from triggering inflammation.

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Built on

Genetic code crackedRecorded · 1961enables
Recombinant DNARecorded · 1973requires
DNA sequencingRecorded · 1977requires

Led to

mRNA vaccinesRecorded · 2020enables
Gene editing made for one patientRecorded · 2025requires
Most infectious disease eliminatedForecast · ~2065requires

Sources & evidence

Additional source

Dataset updated 2026-10-18. This individual record has not been separately re-reviewed.