Pharmaceuticals · Projected milestone
One-shot cures for chronic disease
55% by 2035 · including earlier years
The year is an editorial timing estimate. The percentage applies to occurrence by the stated deadline. These estimates are not calibrated odds.
Single gene or cell therapies replace lifelong pills for common conditions.
Explore this milestone on the interactive mapWhat the forecast means
Milestone stage: milestone (legacy definition)
Completion criteria: Legacy milestone: refine the observable threshold before resolving.
This page describes a forecast, rather than an achieved result. Read the methodology and assumptions.
Built on
- Gene therapyRecorded · 1990enables
- First CRISPR therapyRecorded · 2023enables
- Gene editing made for one patientRecorded · 2025enables
- Stem-cell-derived cell therapyRecorded · 2025enables
- Twice-yearly HIV preventionRecorded · 2025enables
- VERVE-102 in-body cholesterol editing demonstratedRecorded · 2026enables
- Once-yearly HIV prevention shotForecast · ~2028enables
Led to
No connections of this kind are recorded.
Sources & evidence
No individual source links are recorded for this milestone. Source coverage and review status vary across the atlas.
Dataset updated 2026-10-18. This individual record has not been separately re-reviewed.